Gp6 ELISA Kit for Mouse(Mus musculus) | EIAab.comGp6 ELISA Kit for Mouse(Mus musculus)

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Gp6 (Gene name),

Platelet glycoprotein VI (Protein name ), GPVI_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Gp6;

Protein name:

Platelet glycoprotein VI(GPVI);

Alternative:

Glycoprotein 5;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Associated with Fc receptor gamma chain. The GPVI-FcRgamma complex is associated with the Src kinase family Fyn and Lyn.

Function:

Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.

Subcellular Location:

Membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

313

Sequence:

50:

100:

150:

200:

250:

300:

313:

RALQRPLPPL | PLA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P0C191

SMR:

P0C191

Pfam:

PF00047

KEGG:

mmu:243816

UniGene:

Mm.248662

Uniprot:

P0C191

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ELISA Kit for Mouse GPVI

Cat.:

E2206h

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Packing:

96T

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ELISA Kit for Mouse GPVI

Cat.:

E2206m

Price:

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Mouse GPVI

Cat.:

U2206h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse GPVI

Cat.:

U2206m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse GPVI

Cat.:

P2206Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse GPVI

Cat.:

P2206Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse GPVI

Protein for Mouse GPVI

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily."
Jandrot-Perrus M. , Busfield S. , Lagrue A.-H. , Xiong X. , Debili N. , Chickering T. , Le Couedic J.-P. , Goodearl A. , Dussault B. , Fraser C. , Vainchenker W. , Villeval J.-L.
Blood96:1798-1807(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;INTERACTION WITH FC RECEPTOR GAMMA CHAIN;DEVELOPMENTAL STAGE
tissue: Megakaryocyte.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"The glycoprotein VI-phospholipase Cgamma2 signaling pathway controls thrombus formation induced by collagen and tissue factor in vitro and in vivo."
Munnix I.C. , Strehl A. , Kuijpers M.J. , Auger J.M. , van der Meijden P.E. , van Zandvoort M.A. , oude Egbrink M.G. , Nieswandt B. , Heemskerk J.W.
Arterioscler. Thromb. Vasc. Biol.25:2673-2678(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
4.

"GPVI-deficient mice lack collagen responses and are protected against experimentally induced pulmonary thromboembolism."
Lockyer S. , Okuyama K. , Begum S. , Le S. , Sun B. , Watanabe T. , Matsumoto Y. , Yoshitake M. , Kambayashi J. , Tandon N.N.
Thromb. Res.118:371-380(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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